Wednesday, February 23, 2011

How does a person inherit this genetic disorder? Is it dominant or recessive? Is it genetic or chromosomal?

To inherit Cystic Fibrosis, which is a genetic disorder, both of the child’s parents had to of had a gene defeat that they passed on to their offspring.  A child will inherit this genetic disorder only if he/she inherits both of the defective copies of the gene.  The defective gene that causes Cystic Fibrosis is located on chromosome 7.  Chromosome 7 controls the normal production of a protein called Cystic Fibrosis Transmembrane Regulator (CFTR).  A mutation on this gene leads to defective CFTR production.  Which means that the child had a one: four chance of inheriting the disorder and was in that 25%.   

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