Sunday, February 27, 2011

If this disease is genetic-- what are the possible genotypes of the parents? If the disease is a chromosomal abnormality, describe the abnormality?

Cystic Fibrosis is a genetic disease that is autosomal recessive.  Therefore both of the child’s parents had to have been heterozygous (carriers) for Cystic Fibrosis.  Also both of the parents had to of passed on their recessive gene to their child.  Below is an example of what the parent’s genotypes HAD to of been….                        

FF
Ff
Ff
ff
                                                         
                             
Cystic Fibrosis is also a chromosomal abnormality of 1 gene (Chromosome 7).  Chromosome 7 controls the normal production of CFTR.  A person with Cystic Fibrosis has absent or defective CFTR production which leads up to mucus in lungs and problems with pancreas function and food absorption. 

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